H46Y (p.His46Tyr) variant of CYP17A1 (P05093)
H46Y (p.His46Tyr) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
H46Y (p.His46Tyr) variant details
- p.His46Tyr
- TOPMed rs894320518
- gnomAD rs894320518
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.19
- CADD 16.00
- PolyPhen-2 0.67
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available