G90D (p.Gly90Asp) variant of CYP17A1 (P05093)
G90D (p.Gly90Asp) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
G90D (p.Gly90Asp) variant details
- p.Gly90Asp
- ExAC rs778389140
- TOPMed rs778389140
- gnomAD rs778389140
- Missense
- Variant Prioritization Score for Impact Estimate 0.807
- REVEL 0.82
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available