G77S (p.Gly77Ser) variant of CYP17A1 (P05093)
G77S (p.Gly77Ser) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G77S (p.Gly77Ser) variant details
- p.Gly77Ser
- 1000Genomes rs61754265
- ESP rs61754265
- ExAC rs61754265
- TOPMed rs61754265
- Missense
- Variant Prioritization Score for Impact Estimate 0.468
- REVEL 0.33
- CADD 22.60
- PolyPhen-2 0.85
- SIFT 0.19
- Most common in the 1KG:GWD population (allele frequency 0.0043)
- Structural context available