D137N (p.Asp137Asn) variant of CYP17A1 (P05093)
D137N (p.Asp137Asn) in CYP17A1 (P05093) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
D137N (p.Asp137Asn) variant details
- p.Asp137Asn
- gnomAD rs1192632122
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- REVEL 0.34
- CADD 20.80
- PolyPhen-2 0.29
- SIFT 0.10
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available