R27T (p.Arg27Thr) variant of CYP11B1 (P15538)
R27T (p.Arg27Thr) in CYP11B1 (P15538) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R27T (p.Arg27Thr) variant details
- p.Arg27Thr
- ExAC rs768585386
- TOPMed rs768585386
- gnomAD rs768585386
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.10
- CADD 6.06
- PolyPhen-2 0.02
- SIFT 0.36
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available