P77S (p.Pro77Ser) variant of CYP11B1 (P15538)
P77S (p.Pro77Ser) in CYP11B1 (P15538) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
P77S (p.Pro77Ser) variant details
- p.Pro77Ser
- ExAC rs750931191
- TOPMed rs750931191
- gnomAD rs750931191
- Missense
- Variant Prioritization Score for Impact Estimate 0.569
- REVEL 0.51
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available