L66M (p.Leu66Met) variant of CYP11B1 (P15538)
L66M (p.Leu66Met) in CYP11B1 (P15538) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
L66M (p.Leu66Met) variant details
- p.Leu66Met
- ExAC rs763658052
- TOPMed rs763658052
- gnomAD rs763658052
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.35
- CADD 22.50
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available