L3F (p.Leu3Phe) variant of CYP11B1 (P15538)
L3F (p.Leu3Phe) in CYP11B1 (P15538) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
L3F (p.Leu3Phe) variant details
- p.Leu3Phe
- ExAC rs777199047
- gnomAD rs777199047
- Missense
- Variant Prioritization Score for Impact Estimate 0.0819
- REVEL 0.09
- CADD 0.20
- PolyPhen-2 0.01
- SIFT 0.79
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available