Y7D (p.Tyr7Asp) variant of CXCR4 (C-X-C chemokine receptor type 4)
Y7D (p.Tyr7Asp) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
Y7D (p.Tyr7Asp) variant details
- p.Tyr7Asp
- gnomAD 2-136115909-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.06
- MetaLR 0.09
- MetaSVM -1.02
- CADD 19.50
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available