Y12Y (p.Tyr12Tyr) variant of CXCR4 (C-X-C chemokine receptor type 4)
Y12Y (p.Tyr12Tyr) in CXCR4 (C-X-C chemokine receptor type 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
Y12Y (p.Tyr12Tyr) variant details
- p.Tyr12Tyr
- rs1423911335
- gnomAD 2-136115892-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.616
- CADD 8.32
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available