T73M (p.Thr73Met) variant of CXCR4 (C-X-C chemokine receptor type 4)
T73M (p.Thr73Met) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
T73M (p.Thr73Met) variant details
- p.Thr73Met
- TOPMed rs943396331
- Missense
- Variant Prioritization Score for Impact Estimate 0.623
- REVEL 0.59
- MetaLR 0.28
- MetaSVM -0.34
- CADD 29.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available