T43N (p.Thr43Asn) variant of CXCR4 (C-X-C chemokine receptor type 4)
T43N (p.Thr43Asn) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T43N (p.Thr43Asn) variant details
- p.Thr43Asn
- ExAC rs778969048
- TOPMed rs778969048
- gnomAD rs778969048
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.19
- MetaLR 0.25
- MetaSVM -0.52
- CADD 25.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available