T13S (p.Thr13Ser) variant of CXCR4 (C-X-C chemokine receptor type 4)
T13S (p.Thr13Ser) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
T13S (p.Thr13Ser) variant details
- p.Thr13Ser
- gnomAD 2-136115890-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.17
- MetaLR 0.12
- MetaSVM -0.98
- CADD 19.50
- PolyPhen-2 0.01
- SIFT 0.97
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available