T13A (p.Thr13Ala) variant of CXCR4 (C-X-C chemokine receptor type 4)
T13A (p.Thr13Ala) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T13A (p.Thr13Ala) variant details
- p.Thr13Ala
- ExAC rs762966305
- gnomAD rs762966305
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.08
- MetaLR 0.12
- MetaSVM -0.97
- CADD 19.30
- PolyPhen-2 0.05
- SIFT 0.09
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available