P42R (p.Pro42Arg) variant of CXCR4 (C-X-C chemokine receptor type 4)
P42R (p.Pro42Arg) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
P42R (p.Pro42Arg) variant details
- p.Pro42Arg
- gnomAD rs1268474896
- Missense
- Variant Prioritization Score for Impact Estimate 0.699
- REVEL 0.74
- MetaLR 0.30
- MetaSVM -0.37
- CADD 29.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available