P27R (p.Pro27Arg) variant of CXCR4 (C-X-C chemokine receptor type 4)
P27R (p.Pro27Arg) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
P27R (p.Pro27Arg) variant details
- p.Pro27Arg
- rs759904341
- gnomAD 2-136115929-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- CADD 15.80
- SIFT 0.20
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available
- Literature evidence available