P27L (p.Pro27Leu) variant of CXCR4 (C-X-C chemokine receptor type 4)
P27L (p.Pro27Leu) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
P27L (p.Pro27Leu) variant details
- p.Pro27Leu
- rs759904341
- gnomAD 2-136115929-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- CADD 16.00
- SIFT 0.99
- Most common in the HGDP:PALESTINIAN population (allele frequency 0.013)
- Structural context available
- Literature evidence available