P27H (p.Pro27His) variant of CXCR4 (C-X-C chemokine receptor type 4)
P27H (p.Pro27His) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
P27H (p.Pro27His) variant details
- p.Pro27His
- gnomAD 2-136115923-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- CADD 22.70
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available