P27A (p.Pro27Ala) variant of CXCR4 (C-X-C chemokine receptor type 4)
P27A (p.Pro27Ala) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
P27A (p.Pro27Ala) variant details
- p.Pro27Ala
- rs767838620
- gnomAD 2-136115930-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- CADD 11.70
- SIFT 0.67
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available