N11S (p.Asn11Ser) variant of CXCR4 (C-X-C chemokine receptor type 4)
N11S (p.Asn11Ser) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
N11S (p.Asn11Ser) variant details
- p.Asn11Ser
- cosmic curated COSV54016
- gnomAD rs1360006297
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.10
- MetaLR 0.14
- MetaSVM -1.08
- CADD 23.30
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available