M72K (p.Met72Lys) variant of CXCR4 (C-X-C chemokine receptor type 4)
M72K (p.Met72Lys) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
M72K (p.Met72Lys) variant details
- p.Met72Lys
- gnomAD 2-136115713-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.41
- MetaLR 0.17
- MetaSVM -0.90
- CADD 24.40
- PolyPhen-2 0.34
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available