M24V (p.Met24Val) variant of CXCR4 (C-X-C chemokine receptor type 4)
M24V (p.Met24Val) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes structural context.
M24V (p.Met24Val) variant details
- p.Met24Val
- rs1684873120
- ClinGen CA348660205
- ClinVar RCV003515696
- TOPMed rs1684873120
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- AlphaMissense 0.07
- MetaLR 0.09
- MetaSVM -1.06
- PolyPhen-2 0.00
- SIFT 0.20
- MutPred 0.22
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available