M16T (p.Met16Thr) variant of CXCR4 (C-X-C chemokine receptor type 4)
M16T (p.Met16Thr) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
M16T (p.Met16Thr) variant details
- p.Met16Thr
- gnomAD 2-136115881-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.08
- MetaLR 0.11
- MetaSVM -0.99
- CADD 15.80
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available