K68Q (p.Lys68Gln) variant of CXCR4 (C-X-C chemokine receptor type 4)
K68Q (p.Lys68Gln) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
K68Q (p.Lys68Gln) variant details
- p.Lys68Gln
- TOPMed rs1481575745
- gnomAD rs1481575745
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.57
- MetaLR 0.48
- MetaSVM 0.01
- CADD 28.30
- PolyPhen-2 0.93
- SIFT 0.05
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available