I60N (p.Ile60Asn) variant of CXCR4 (C-X-C chemokine receptor type 4)
I60N (p.Ile60Asn) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
I60N (p.Ile60Asn) variant details
- p.Ile60Asn
- gnomAD rs1374176769
- Missense
- Variant Prioritization Score for Impact Estimate 0.745
- REVEL 0.81
- MetaLR 0.68
- MetaSVM 0.56
- CADD 28.90
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available