G64A (p.Gly64Ala) variant of CXCR4 (C-X-C chemokine receptor type 4)
G64A (p.Gly64Ala) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
G64A (p.Gly64Ala) variant details
- p.Gly64Ala
- gnomAD rs1479506035
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.16
- MetaLR 0.14
- MetaSVM -1.03
- CADD 24.00
- PolyPhen-2 0.56
- SIFT 0.16
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available