G3E (p.Gly3Glu) variant of CXCR4 (C-X-C chemokine receptor type 4)
G3E (p.Gly3Glu) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
G3E (p.Gly3Glu) variant details
- p.Gly3Glu
- TOPMed rs1684968641
- Missense
- Variant Prioritization Score for Impact Estimate 0.0986
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.05
- CADD 8.65
- PolyPhen-2 0.02
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available