D22G (p.Asp22Gly) variant of CXCR4 (C-X-C chemokine receptor type 4)
D22G (p.Asp22Gly) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
D22G (p.Asp22Gly) variant details
- p.Asp22Gly
- gnomAD 2-136115863-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.03
- MetaLR 0.12
- MetaSVM -0.99
- CADD 22.50
- PolyPhen-2 0.02
- SIFT 0.43
- Population evidence available
- Structural context available
- Literature evidence available