D20H (p.Asp20His) variant of CXCR4 (C-X-C chemokine receptor type 4)
D20H (p.Asp20His) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
D20H (p.Asp20His) variant details
- p.Asp20His
- gnomAD 2-136115870-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- REVEL 0.32
- MetaLR 0.30
- MetaSVM -0.53
- CADD 26.10
- PolyPhen-2 0.94
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available