D10V (p.Asp10Val) variant of CXCR4 (C-X-C chemokine receptor type 4)
D10V (p.Asp10Val) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
D10V (p.Asp10Val) variant details
- p.Asp10Val
- cosmic curated COSV10438
- TOPMed rs1289282733
- gnomAD rs1289282733
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.27
- MetaLR 0.21
- MetaSVM -0.94
- CADD 24.70
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available