D10G (p.Asp10Gly) variant of CXCR4 (C-X-C chemokine receptor type 4)
D10G (p.Asp10Gly) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
D10G (p.Asp10Gly) variant details
- p.Asp10Gly
- gnomAD 2-136115899-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.25
- MetaLR 0.20
- MetaSVM -1.05
- CADD 23.60
- PolyPhen-2 0.11
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available