D10E (p.Asp10Glu) variant of CXCR4 (C-X-C chemokine receptor type 4)
D10E (p.Asp10Glu) in CXCR4 (C-X-C chemokine receptor type 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
D10E (p.Asp10Glu) variant details
- p.Asp10Glu
- gnomAD 2-136115898-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.10
- MetaLR 0.12
- MetaSVM -1.01
- CADD 16.30
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available