S59G (p.Ser59Gly) variant of CUX1 (Homeobox protein cut-like 1)
S59G (p.Ser59Gly) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, experimental measurements, and structural context.
S59G (p.Ser59Gly) variant details
- p.Ser59Gly
- TOPMed rs989872151
- gnomAD rs989872151
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.23
- MetaLR 0.17
- MetaSVM -0.79
- CADD 29.30
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- CUX1 CUT domain domainome 1.0: score -0.006