R8M (p.Arg8Met) variant of CUX1 (Homeobox protein cut-like 1)
R8M (p.Arg8Met) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R8M (p.Arg8Met) variant details
- p.Arg8Met
- gnomAD 7-101817662-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.06
- MetaLR 0.04
- MetaSVM -1.06
- CADD 18.20
- PolyPhen-2 0.00
- SIFT 0.04
- Population evidence available
- Structural context available
- CUX1 Homeobox domain domainome 1.0: score -0.516
- Literature evidence available