R11S (p.Arg11Ser) variant of CUX1 (Homeobox protein cut-like 1)
R11S (p.Arg11Ser) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, experimental measurements, and structural context.
R11S (p.Arg11Ser) variant details
- p.Arg11Ser
- ESP rs140709702
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.23
- MetaLR 0.04
- MetaSVM -1.10
- CADD 22.70
- PolyPhen-2 0.17
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- CUX1 Homeobox domain domainome 1.0: score -0.379