R11G (p.Arg11Gly) variant of CUX1 (Homeobox protein cut-like 1)
R11G (p.Arg11Gly) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, experimental measurements, and structural context.
R11G (p.Arg11Gly) variant details
- p.Arg11Gly
- TOPMed rs1177297232
- gnomAD rs1177297232
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.34
- MetaLR 0.05
- MetaSVM -1.12
- CADD 24.80
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- CUX1 Homeobox domain domainome 1.0: score -0.379