L9S (p.Leu9Ser) variant of CUX1 (Homeobox protein cut-like 1)
L9S (p.Leu9Ser) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L9S (p.Leu9Ser) variant details
- p.Leu9Ser
- gnomAD 7-101817665-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.11
- MetaLR 0.08
- MetaSVM -1.04
- CADD 20.70
- PolyPhen-2 0.04
- SIFT 0.03
- Population evidence available
- Structural context available
- CUX1 Homeobox domain domainome 1.0: score -0.706
- Literature evidence available