L2F (p.Leu2Phe) variant of CUX1 (Homeobox protein cut-like 1)
L2F (p.Leu2Phe) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L2F (p.Leu2Phe) variant details
- p.Leu2Phe
- gnomAD 7-101817645-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.10
- MetaLR 0.09
- MetaSVM -0.99
- CADD 19.90
- PolyPhen-2 0.35
- SIFT 0.09
- Population evidence available
- Structural context available
- CUX1 CUT domain domainome 1.0: score -0.329
- Literature evidence available