L20S (p.Leu20Ser) variant of CUX1 (Homeobox protein cut-like 1)
L20S (p.Leu20Ser) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L20S (p.Leu20Ser) variant details
- p.Leu20Ser
- gnomAD 7-101816080-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.579
- CADD 26.70
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- CUX1 Homeobox domain domainome 1.0: score -0.137
- Literature evidence available