E75G (p.Glu75Gly) variant of CUX1 (Homeobox protein cut-like 1)
E75G (p.Glu75Gly) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, experimental measurements, and structural context.
E75G (p.Glu75Gly) variant details
- p.Glu75Gly
- gnomAD rs1361406242
- Missense
- Variant Prioritization Score for Impact Estimate 0.633
- REVEL 0.58
- MetaLR 0.72
- MetaSVM 0.56
- CADD 27.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- CUX1 CUT domain domainome 1.0: score -0.0274