D14N (p.Asp14Asn) variant of CUX1 (Homeobox protein cut-like 1)
D14N (p.Asp14Asn) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, experimental measurements, and structural context.
D14N (p.Asp14Asn) variant details
- p.Asp14Asn
- ExAC rs756778760
- gnomAD rs756778760
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.12
- MetaLR 0.25
- MetaSVM -0.83
- CADD 25.00
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- CUX1 Homeobox domain domainome 1.0: score -0.879