C3Y (p.Cys3Tyr) variant of CUX1 (Homeobox protein cut-like 1)
C3Y (p.Cys3Tyr) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
C3Y (p.Cys3Tyr) variant details
- p.Cys3Tyr
- gnomAD 7-101817647-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.22
- MetaLR 0.19
- MetaSVM -0.62
- CADD 19.80
- PolyPhen-2 0.96
- SIFT 0.01
- Population evidence available
- Structural context available
- CUX1 CUT domain domainome 1.0: score -0.227
- Literature evidence available