A7S (p.Ala7Ser) variant of CUX1 (Homeobox protein cut-like 1)
A7S (p.Ala7Ser) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A7S (p.Ala7Ser) variant details
- p.Ala7Ser
- gnomAD 7-101817658-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.06
- MetaLR 0.03
- MetaSVM -1.07
- CADD 18.50
- PolyPhen-2 0.02
- SIFT 0.11
- Population evidence available
- Structural context available
- CUX1 CUT domain domainome 1.0: score -0.5
- Literature evidence available