A15G (p.Ala15Gly) variant of CUX1 (Homeobox protein cut-like 1)
A15G (p.Ala15Gly) in CUX1 (Homeobox protein cut-like 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A15G (p.Ala15Gly) variant details
- p.Ala15Gly
- ExAC rs778368760
- TOPMed rs778368760
- gnomAD rs778368760
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.07
- MetaLR 0.10
- MetaSVM -1.07
- CADD 25.70
- PolyPhen-2 0.36
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- CUX1 Homeobox domain domainome 1.0: score -0.345