Y29F (p.Tyr29Phe) variant of CUL3 (Cullin-3)
Y29F (p.Tyr29Phe) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
Y29F (p.Tyr29Phe) variant details
- p.Tyr29Phe
- Ensembl rs1694761916
- Missense
- Variant Prioritization Score for Impact Estimate 0.431
- REVEL 0.32
- CADD 22.80
- PolyPhen-2 0.09
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available