T8P (p.Thr8Pro) variant of CUL3 (Cullin-3)
T8P (p.Thr8Pro) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
T8P (p.Thr8Pro) variant details
- p.Thr8Pro
- gnomAD rs1323366532
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.13
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available