T24S (p.Thr24Ser) variant of CUL3 (Cullin-3)
T24S (p.Thr24Ser) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T24S (p.Thr24Ser) variant details
- p.Thr24Ser
- gnomAD rs1694762152
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.18
- CADD 19.00
- PolyPhen-2 0.01
- SIFT 0.78
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available