T24I (p.Thr24Ile) variant of CUL3 (Cullin-3)
T24I (p.Thr24Ile) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
T24I (p.Thr24Ile) variant details
- p.Thr24Ile
- Ensembl rs2106305230
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.33
- CADD 23.90
- PolyPhen-2 0.55
- SIFT 0.14
- Population evidence available
- Structural context available