T14N (p.Thr14Asn) variant of CUL3 (Cullin-3)
T14N (p.Thr14Asn) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
T14N (p.Thr14Asn) variant details
- p.Thr14Asn
- ExAC rs767631760
- gnomAD rs767631760
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.08
- CADD 20.20
- PolyPhen-2 0.06
- SIFT 0.50
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available