S5R (p.Ser5Arg) variant of CUL3 (Cullin-3)
S5R (p.Ser5Arg) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S5R (p.Ser5Arg) variant details
- p.Ser5Arg
- Ensembl rs2106331366
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.03
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.17
- Population evidence available
- Structural context available